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Effect of echinacoside on kidney fibrosis by inhibition of TGF-β1/Smads signaling pathway in the db/db mice model of diabetic nephropathy

Kidney fibrosis and renal tubular epithelial-to-mesenchymal transition (EMT) are the main pathological changes of diabetic nephropathy (DN), which eventually leads to end-stage renal disease. Previous studies have suggested that echinacoside (ECH) is antifibrotic in the liver. However, the effect of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Drug Des Devel Ther
Egile Nagusiak: Tang, Fengjuan, Hao, Yarong, Zhang, Xue, Qin, Jian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Dove Medical Press 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614741/
https://ncbi.nlm.nih.gov/pubmed/29033543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S143805
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