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Development of a subunit vaccine for prevention of Clostridium difficile associated diseases: Biophysical characterization of toxoids A and B

Inactivation of bacterial toxins for use in human vaccines traditionally is achieved by treatment with formaldehyde. In contrast, the bivalent experimental vaccine for the prevention of C. difficile infections (CDI) that is currently being evaluated in clinical trials was produced using a different...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Gribenko, Alexey, Severina, Elena, Sidhu, Maninder K., Jansen, Kathrin U., Green, Bruce A., Matsuka, Yury V.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614615/
https://ncbi.nlm.nih.gov/pubmed/28956005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.12.015
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