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Tumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic Agents
Antimitotic agents, including Taxol, disrupt microtubule dynamics and cause a protracted mitotic arrest and subsequent cell death. Despite the broad utility of these drugs in breast cancer and other tumor types, clinical response remains variable. Tumor-associated macrophages (TAMs) suppress the dur...
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| Veröffentlicht in: | Cell Rep |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5614506/ https://ncbi.nlm.nih.gov/pubmed/28380350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.03.038 |
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