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A 3D-psoriatic skin model for dermatological testing: The impact of culture conditions

BACKGROUND: Inadequate representation of the human tissue environment during a preclinical screen can result in inaccurate predictions of compound effects. Consequently, pharmaceutical investigators are searching for preclinical models that closely resemble original tissue for predicting clinical ou...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Duque-Fernandez, Alexandra, Gauthier, Lydia, Simard, Mélissa, Jean, Jessica, Gendreau, Isabelle, Morin, Alexandre, Soucy, Jacques, Auger, Michèle, Pouliot, Roxane.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614463/
https://ncbi.nlm.nih.gov/pubmed/28955966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.09.012
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