The C-terminal domain of glyceraldehyde 3-phosphate dehydrogenase plays an important role in suppression of tRNA(Lys3) packaging into human immunodeficiency virus type-1 particles

Human immunodeficiency virus type-1 (HIV-1) requires the packaging of human tRNA(Lys3) as a primer for effective viral reverse transcription. Previously, we reported that glyceraldehyde 3-phosphate dehydrogenase (GAPDH) suppresses the packaging efficiency of tRNA(Lys3). Although the binding of GAPDH...

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Veröffentlicht in:Biochem Biophys Rep
Hauptverfasser: Kishimoto, Naoki, Onitsuka-Kishimoto, Ayano, Iga, Nozomi, Takamune, Nobutoki, Shoji, Shozo, Misumi, Shogo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614461/
https://ncbi.nlm.nih.gov/pubmed/28955972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.09.015
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