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A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research

Recent studies that compared transcriptomic datasets of human diseases with datasets from mouse models using traditional gene-to-gene comparison techniques resulted in contradictory conclusions regarding the relevance of animal models for translational research. A major reason for the discrepancies...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Weidner, Christopher, Steinfath, Matthias, Wistorf, Elisa, Oelgeschläger, Michael, Schneider, Marlon R., Schönfelder, Gilbert
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614334/
https://ncbi.nlm.nih.gov/pubmed/28872130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55768
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