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Sclerostin antibodies in osteoporosis: latest evidence and therapeutic potential
Sclerostin is an osteocyte-derived glycoprotein that inhibits Wnt/β-catenin signaling and activation of osteoblast function, thereby inhibiting bone formation. It plays a vital role in the regulation of skeletal growth. In adults, sclerostin secretion is modulated by skeletal loading (increased secr...
保存先:
| 出版年: | Ther Adv Musculoskelet Dis |
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| 第一著者: | |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
SAGE Publications
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5613857/ https://ncbi.nlm.nih.gov/pubmed/28974988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759720X17726744 |
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