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Generation and Characterization of α9 and α10 Nicotinic Acetylcholine Receptor Subunit Knockout Mice on a C57BL/6J Background

We generated constitutive knockout mouse models for the α9 and α10 nicotinic acetylcholine receptor (nAChR) subunits by derivation from conditional knockouts by breeding with CRE deleter mice. We then backcrossed them onto a C57BL/6J genetic background. In this manuscript, we report the generation o...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Morley, Barbara J., Dolan, David F., Ohlemiller, Kevin K., Simmons, Dwayne D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613126/
https://ncbi.nlm.nih.gov/pubmed/28983232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00516
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