Therapeutic Effectiveness of Anti-RAGE Antibody Administration in a Rat Model of Crush Injury

Crush injury patients often have systemic inflammatory response syndrome that leads to multiple organ failure. Receptor for advanced glycation endproducts (RAGE) functions as a pattern recognition receptor that regulates inflammation. We evaluated the effects of anti-RAGE antibody in a crush injury...

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Udgivet i:Sci Rep
Main Authors: Matsumoto, Hisatake, Matsumoto, Naoya, Shimazaki, Junya, Nakagawa, Junichiro, Imamura, Yukio, Yamakawa, Kazuma, Yamada, Tomoki, Ikeda, Mitsunori, Hiraike, Hiroko, Ogura, Hiroshi, Shimazu, Takeshi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613014/
https://ncbi.nlm.nih.gov/pubmed/28947744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12065-4
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