Premature contractions of the bladder are suppressed by interactions between TRPV4 and SK3 channels in murine detrusor PDGFRα(+) cells

During filling, urinary bladder volume increases dramatically with little change in pressure. This is accomplished by suppressing contractions of the detrusor muscle that lines the bladder wall. Mechanisms responsible for regulating detrusor contraction during filling are poorly understood. Here we...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Lee, Haeyeong, Koh, Byoung H., Peri, Lauren E., Corrigan, Robert D., Lee, Hyun-Tai, George, Nikita E., Bhetwal, Bhupal P., Xie, Yeming, Perrino, Brian A., Chai, Toby C., Sanders, Kenton M., Koh, Sang Don
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613012/
https://ncbi.nlm.nih.gov/pubmed/28947806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12561-7
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