Decreased Surface Expression of the δ Subunit of the GABA(A) Receptor Contributes to Reduced Tonic Inhibition in Dentate Granule Cells in a Mouse Model of Fragile X Syndrome

While numerous changes in the GABA system have been identified in models of Fragile X Syndrome (FXS), alterations in subunits of the GABA(A) receptors (GABA(A)Rs) that mediate tonic inhibition are particularly intriguing. Considering the key role of tonic inhibition in controlling neuronal excitabil...

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Publicado no:Exp Neurol
Main Authors: Zhang, Nianhui, Peng, Zechun, Tong, Xiaoping, Lindemeyer, A. Kerstin, Cetina, Yliana, Huang, Christine S., Olsen, Richard W., Otis, Thomas S., Houser, Carolyn R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612918/
https://ncbi.nlm.nih.gov/pubmed/28822839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2017.08.008
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