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Developing HiPSC Derived Serum Free Embryoid Bodies for the Interrogation of 3-D Stem Cell Cultures Using Physiologically Relevant Assays

Although a number of in vitro disease models have been developed using hiPSCs, one limitation is that these two-dimensional (2-D) systems may not represent the underlying cytoarchitectural and functional complexity of the affected individuals carrying suspected disease variants. Conventional 2-D mod...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Phillips, Andre W., Nestor, Jonathan E., Nestor, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612555/
https://ncbi.nlm.nih.gov/pubmed/28784957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55799
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