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Isolation of Circulating Tumor Cells in an Orthotopic Mouse Model of Colorectal Cancer

Despite the advantages of easy applicability and cost-effectiveness, subcutaneous mouse models have severe limitations and do not accurately simulate tumor biology and tumor cell dissemination. Orthotopic mouse models have been introduced to overcome these limitations; however, such models are techn...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Kochall, Susan, Thepkaysone, May-Linn, García, Sebastián A., Betzler, Alexander M., Weitz, Jürgen, Reissfelder, Christoph, Schölch, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612534/
https://ncbi.nlm.nih.gov/pubmed/28745637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55357
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