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Small-Molecule Screens: A Gateway to Cancer Therapeutic Agents with Case Studies of Food and Drug Administration–Approved Drugs

High-throughput screening (HTS) of small-molecule libraries accelerates the discovery of chemical leads to serve as starting points for probe or therapeutic development. With this approach, thousands of unique small molecules, representing a diverse chemical space, can be rapidly evaluated by biolog...

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Dettagli Bibliografici
Pubblicato in:Pharmacol Rev
Autori principali: Coussens, Nathan P., Braisted, John C., Peryea, Tyler, Sittampalam, G. Sitta, Simeonov, Anton, Hall, Matthew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612261/
https://ncbi.nlm.nih.gov/pubmed/28931623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.117.013755
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