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Drosophila PAF1 modulates PIWI/piRNA silencing capacity
To test the directness of factors in initiating PIWI-directed gene silencing, we employed a Piwi-interacting RNA (piRNA)-targeted reporter assay in Drosophila OSS cells [1]. This assay confirmed direct silencing roles for piRNA biogenesis factors and PIWI-associated factors [2–12], but suggested tha...
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| Publié dans: | Curr Biol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5611886/ https://ncbi.nlm.nih.gov/pubmed/28844648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.07.052 |
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