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Hepatic 11β-hydroxysteroid dehydrogenase type 1 activity in obesity and type 2 diabetes using a novel triple tracer cortisol technique

AIMS/HYPOTHESIS: Dysregulation of 11β-hydroxysteroid dehydrogenase (11β-HSD) enzyme activities are implicated in the pathogenesis of obesity and insulin resistance. The aim of the study was to determine whether hepatic 11β-HSD type 1 (11β-HSD-1) enzyme activity differs in people with and without obe...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Dube, Simmi, Norby, Barbara, Pattan, Vishwanath, Lingineni, Ravi K., Singh, Ravinder J., Carter, Rickey E., Basu, Ananda, Basu, Rita
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611844/
https://ncbi.nlm.nih.gov/pubmed/24771091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-014-3240-x
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