Trehalose Improves Cognition in the Transgenic Tg2576 Mouse Model of Alzheimer’s Disease

This study assessed the therapeutic utility of the autophagy enhancing stable disaccharide trehalose in the Tg2576 transgenic mouse model of Alzheimer’s disease (AD) via an oral gavage of a 2% trehalose solution for 31 days. Furthermore, as AD is a neurodegenerative condition in which the transition...

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Bibliografiske detaljer
Udgivet i:J Alzheimers Dis
Main Authors: Portbury, Stuart D., Hare, Dominic J., Sgambelloni, Charlotte, Perronnes, Kali, Portbury, Ashley J., Finkelstein, David I., Adlard, Paul A.
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611803/
https://ncbi.nlm.nih.gov/pubmed/28869469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-170322
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