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Phospho-Tau Accumulation and Structural Alterations of the Golgi Apparatus of Cortical Pyramidal Neurons in the P301S Tauopathy Mouse Model

The Golgi apparatus (GA) is a highly dynamic organelle involved in the processing and sorting of cellular proteins. In Alzheimer’s disease (AD), it has been shown to decrease in size and become fragmented in neocortical and hippocampal neuronal subpopulations. This fragmentation and decrease in size...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Antón-Fernández, Alejandro, Merchán-Rubira, Jesús, Avila, Jesús, Hernández, Félix, DeFelipe, Javier, Muñoz, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611801/
https://ncbi.nlm.nih.gov/pubmed/28922155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-170332
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