Influence of genetic variants on renal uric acid handling in response to frusemide: an acute intervention study

OBJECTIVES: Genetic variation in the renal urate transporters SLC2A9 (GLUT9) and SLC22A11 (OAT4) has been reported to interact with diuretics to increase the risk of developing gout. The aim of this study was to determine whether variation in SLC2A9 or SLC22A11 influences acute renal handling of uri...

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Detalhes bibliográficos
Publicado no:RMD Open
Main Authors: Dalbeth, Nicola, Allan, Jordyn, Gamble, Gregory D, Phipps-Green, Amanda, Flynn, Tanya J, Mihov, Borislav, Horne, Anne, Doughty, Robert, Stamp, Lisa K, Merriman, Tony R
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
Assuntos:
Crystal Arthropathies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611711/
https://ncbi.nlm.nih.gov/pubmed/28951782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/rmdopen-2016-000424
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