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The Evolution, Functions and Applications of the Breast Cancer Genes BRCA1 and BRCA2

BRCA1 and BRCA2 are both tumor suppressors whose mutations are the cause of most hereditary breast cancers. Both genes are highly involved in ensuring genome stability. BRCA1 homologs are found in the plant and animal kingdoms while BRCA2 homologs are additionally found in the fungi kingdom. The ini...

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Detalhes bibliográficos
Publicado no:Cancer Genomics Proteomics
Main Authors: PFEFFER, M. CLAIRE, HO, N. BENJAMIN, SINGH, T.K. AMARESHWAR
Formato: Artigo
Idioma:Inglês
Publicado em: International Institute of Anticancer Research 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611516/
https://ncbi.nlm.nih.gov/pubmed/28870997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/cgp.20040
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