Identification of MPL R102P Mutation in Hereditary Thrombocytosis

The molecular basis of hereditary thrombocytosis is germline mutations affecting the thrombopoietin (TPO)/TPO receptor (MPL)/JAK2 signaling axis. Here, we report one family presenting two cases with a mild thrombocytosis. By sequencing JAK2 and MPL coding exons, we identified a germline MPL R102P he...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Front Endocrinol (Lausanne)
Asıl Yazarlar: Bellanné-Chantelot, Christine, Mosca, Matthieu, Marty, Caroline, Favier, Rémi, Vainchenker, William, Plo, Isabelle
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2017
Konular:
Endocrinology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5611484/
https://ncbi.nlm.nih.gov/pubmed/28979237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2017.00235
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller