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Dose and Schedule Selection of the Oral Proteasome Inhibitor Ixazomib in Relapsed/Refractory Multiple Myeloma: Clinical and Model-Based Analyses

BACKGROUND: The oral proteasome inhibitor ixazomib has been approved by regulatory authorities around the world, including in the United States and the European Union, for the treatment of patients with multiple myeloma (MM) who have received at least one prior therapy, based on the pivotal phase II...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Target Oncol
Hauptverfasser: Gupta, Neeraj, Yang, Huyuan, Hanley, Michael J., Zhang, Steven, Liu, Rachael, Kumar, Shaji, Richardson, Paul G., Skacel, Tomas, Venkatakrishnan, Karthik
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610674/
https://ncbi.nlm.nih.gov/pubmed/28803351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11523-017-0524-3
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