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Coincidental null mutation of Csf2rα in a colony of PI3Kγ-/- mice causes alveolar macrophage deficiency and fatal respiratory viral infection

PI-3-kinases have been identified as key signaling proteins involved in many basic biological processes in health and disease. Transgenic animals have been essential tools to study the underlying molecular mechanisms in this context and have therefore been widely used to elucidate the role of these...

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Bibliografiske detaljer
Udgivet i:J Leukoc Biol
Main Authors: Schneider, Christoph, Nobs, Samuel P., Heer, Alex K., Hirsch, Emilio, Penninger, Josef, Siggs, Owen M., Kopf, Manfred
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610570/
https://ncbi.nlm.nih.gov/pubmed/27468760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4HI0316-157R
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