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Systematic Therapeutic Drug Monitoring for Linezolid: Variability and Clinical Impact
Linezolid serum trough (C(min)) and peak (C(max)) levels were determined prospectively in 90 patients. Adequate exposure was defined as a C(min) of 2 to 8 mg/liter. Therapy was empirical (73.3%) or targeted (26.7%). Wide interindividual variability in linezolid C(min) levels was recorded (0.1 to 25....
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5610525/ https://ncbi.nlm.nih.gov/pubmed/28739788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00687-17 |
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