Comparative Pharmacodynamics of Single-Dose Oritavancin and Daily High-Dose Daptomycin Regimens against Vancomycin-Resistant Enterococcus faecium Isolates in an In Vitro Pharmacokinetic/Pharmacodynamic Model of Infection

There are limited therapeutic options to treat infections caused by vancomycin-resistant Enterococcus faecium (VREfm). The lipoglycopeptide oritavancin exhibits in vitro activity against this pathogen, although its utility against infections caused by VREfm has not been clinically established. In th...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Belley, Adam, Lalonde-Séguin, David, Arhin, Francis F., Moeck, Greg
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610485/
https://ncbi.nlm.nih.gov/pubmed/28784674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01265-17
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