Fluoxetine and thioridazine inhibit efflux and attenuate crystalline biofilm formation by Proteus mirabilis

Proteus mirabilis forms extensive crystalline biofilms on indwelling urethral catheters that block urine flow and lead to serious clinical complications. The Bcr/CflA efflux system has previously been identified as important for development of P. mirabilis crystalline biofilms, highlighting the pote...

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發表在:Sci Rep
Main Authors: Nzakizwanayo, Jonathan, Scavone, Paola, Jamshidi, Shirin, Hawthorne, Joseph A., Pelling, Harriet, Dedi, Cinzia, Salvage, Jonathan P., Hind, Charlotte K., Guppy, Fergus M., Barnes, Lara M., Patel, Bhavik A., Rahman, Khondaker M., Sutton, Mark J., Jones, Brian V.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610337/
https://ncbi.nlm.nih.gov/pubmed/28939900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12445-w
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