Anti-proliferation of triple-negative breast cancer cells with physagulide P: ROS/JNK signaling pathway induces apoptosis and autophagic cell death

Physagulide P (PP), a new natural compound, was isolated from Physalis angulate L. in our laboratory. In this study, we demonstrated that PP potently suppressed cell proliferation by inducing G2/M phase arrest in MDA-MB-231 and MDA-MB-468 cells. Moreover, PP provoked apoptosis by decreasing the mito...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yu, Pei, Zhang, Chao, Gao, Cai-Yun, Ma, Ting, Zhang, Hao, Zhou, Miao-Miao, Yang, Yan-Wei, Yang, Lei, Kong, Ling-Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609982/
https://ncbi.nlm.nih.gov/pubmed/28969050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19299
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