Transmembrane TNF-α promotes activation-induced cell death by forward and reverse signaling

Secretory tumor necrosis factor-alpha (sTNF-α) is known to mediate activation- induced cell death (AICD). However, the role of tmTNF-α in AICD is still obscure. Here, we demonstrated that tmTNF-α expression significantly increased accompanied with enhanced apoptosis during AICD in Jurkat and primary...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Meng, Wang, Jing, Jia, Lingwei, Huang, Jin, He, Cheng, Hu, Fuqing, Yuan, Lifei, Wang, Guihua, Yu, Mingxia, Li, Zhuoya
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609962/
https://ncbi.nlm.nih.gov/pubmed/28969030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19124
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