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Epigenetic regulation of NOTCH1 and NOTCH3 by KMT2A inhibits glioma proliferation
Glioblastomas are among the most fatal brain tumors; however, the molecular determinants of their tumorigenic behavior are not adequately defined. In this study, we analyzed the role of KMT2A in the glioblastoma cell line U-87 MG. KMT2A knockdown promoted cell proliferation. Moreover, it increased t...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5609907/ https://ncbi.nlm.nih.gov/pubmed/28968975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18668 |
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