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Substrate-based near-infrared imaging sensors enable fluorescence lifetime contrast via built-in dynamic fluorescence quenching elements

Enzymatic activity sensing in fluorescence lifetime (FLT) mode with “self-quenched” macromolecular near-infrared (NIR) sensors is a highly promising strategy for in vivo imaging of proteolysis. However, the mechanisms of FLT changes in such substrate-based NIR sensors have not yet been studied. We s...

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Publicat a:ACS Sens
Autors principals: Kumar, Anand T. N., Rice, William L., López, Jessica C., Gupta, Suresh, Goergen, Craig J., Bogdanov, Alexei A.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609830/
https://ncbi.nlm.nih.gov/pubmed/28944290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssensors.5b00252
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