Interactions between calcium intake and polymorphisms in genes essential for calcium reabsorption and risk of colorectal neoplasia in a two-phase study

The SLC8A1 (solute carrier family 8, member 1) gene, encoding Na(+)/Ca(2+) exchanger, is essential in regulating calcium reabsorption and homeostasis. Calcium homeostasis plays a key role in cell proliferation and apoptosis. We hypothesized that polymorphisms in five calcium-regulating genes (SLC8A1...

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Veröffentlicht in:Mol Carcinog
Hauptverfasser: Zhao, Jing, Zhu, Xiangzhu, Shrubsole, Martha J, Ness, Reid M, Hibler, Elizabeth A, Cai, Qiuyin, Long, Jirong, Chen, Zhi, Jiang, Ming, Kabagambe, Edmond K., Zhang, Bing, Hou, Lifang, Smalley, Walter E, Edwards, Todd L., Giovannucci, Edward L., Zheng, Wei, Dai, Qi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609815/
https://ncbi.nlm.nih.gov/pubmed/28544176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22678
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