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Twenty years of menin; emerging opportunities for restoration of transcriptional regulation in MEN1

Since the discovery of the multiple endocrine neoplasia type 1 (MEN1) gene in 1997, elucidation of the molecular function of its protein product, menin, has been a challenge. Biochemical, proteomics, genetics and genomics approaches have identified various potential roles, which converge on gene exp...

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Détails bibliographiques
Publié dans:Endocr Relat Cancer
Auteurs principaux: Dreijerink, Koen M.A., Timmers, Marc, Brown, Myles
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609455/
https://ncbi.nlm.nih.gov/pubmed/28811299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-17-0281
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