Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E)

Cutaneous T-cell lymphoma (CTCL) is an incurable non-Hodgkin lymphoma of the skin-homing T cell. In early-stage disease, lesions are limited to the skin, but in later-stage disease, the tumor cells can escape into the blood, the lymph nodes, and at times the visceral organs. To clarify the genomic b...

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Udgivet i:Blood
Main Authors: Park, Joonhee, Yang, Jingyi, Wenzel, Alexander T., Ramachandran, Akshaya, Lee, Wung J., Daniels, Jay C., Kim, Juhyun, Martinez-Escala, Estela, Amankulor, Nduka, Pro, Barbara, Guitart, Joan, Mendillo, Marc L., Savas, Jeffrey N., Boggon, Titus J., Choi, Jaehyuk
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2017
Fag:
Lymphoid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609333/
https://ncbi.nlm.nih.gov/pubmed/28694326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-02-768234
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