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Effects of ticagrelor in a mouse model of ischemic stroke

Ticagrelor is a direct acting and reversibly binding P2Y12 antagonist approved for the prevention of thromboembolic events. Its potential benefits in ischemic stroke have not been investigated sufficiently. Mice were subjected to 2 hours of transient middle cerebral artery occlusion (MCAO). Mice wer...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Yamauchi, Keita, Imai, Takahiko, Shimazawa, Masamitsu, Iwama, Toru, Hara, Hideaki
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608945/
https://ncbi.nlm.nih.gov/pubmed/28935927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12205-w
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