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Ranolazine promotes muscle differentiation and reduces oxidative stress in C2C12 skeletal muscle cells

PURPOSE: The purpose of this study is to investigate Ranolazine action on skeletal muscle differentiation and mitochondrial oxidative phenomena. Ranolazine, an antianginal drug, which acts blocking the late INaL current, was shown to lower hemoglobin A1c in patients with diabetes. In the present stu...

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Опубликовано в: :Endocrine
Главные авторы: Ileana, Terruzzi, Anna, Montesano, Pamela, Senesi, Fernanda, Vacante, Stefano, Benedini, Livio, Luzi
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608860/
https://ncbi.nlm.nih.gov/pubmed/27933435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12020-016-1181-5
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