Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies

Tauopathies, including Alzheimer’s disease (AD) and other neurodegenerative conditions, are defined by a pathological hallmark: neurofibrillary tangles (NFT). NFT accumulation is thought to be closely linked to cognitive decline in AD. Here, we perform a genome-wide association study for NFT patholo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Psychiatry
Prif Awduron: Chibnik, Lori B, White, Charles C, Mukherjee, Shubhabrata, Raj, Towfique, Yu, Lei, Larson, Eric B., Montine, Thomas J., Keene, C. Dirk, Sonnen, Joshua, Schneider, Julie A., Crane, Paul K., Shulman, Joshua M., Bennett, David A, De Jager, Philip L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608624/
https://ncbi.nlm.nih.gov/pubmed/28322283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2017.20
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg