Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies

Tauopathies, including Alzheimer’s disease (AD) and other neurodegenerative conditions, are defined by a pathological hallmark: neurofibrillary tangles (NFT). NFT accumulation is thought to be closely linked to cognitive decline in AD. Here, we perform a genome-wide association study for NFT patholo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Chibnik, Lori B, White, Charles C, Mukherjee, Shubhabrata, Raj, Towfique, Yu, Lei, Larson, Eric B., Montine, Thomas J., Keene, C. Dirk, Sonnen, Joshua, Schneider, Julie A., Crane, Paul K., Shulman, Joshua M., Bennett, David A, De Jager, Philip L
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608624/
https://ncbi.nlm.nih.gov/pubmed/28322283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2017.20
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados