Early metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo (1)H MR spectroscopy

Melatonin is a promising neuroprotective agent after perinatal hypoxic-ischemic (HI) brain injury. We used in-vivo (1)H magnetic resonance spectroscopy to investigate effects of melatonin treatment on brain metabolism after HI. Postnatal day 7 Sprague-Dawley rats with unilateral HI brain injury were...

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Pubblicato in:PLoS One
Autori principali: Berger, Hester Rijkje, Nyman, Axel K. G., Morken, Tora Sund, Vettukattil, Riyas, Brubakk, Ann-Mari, Widerøe, Marius
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608359/
https://ncbi.nlm.nih.gov/pubmed/28934366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185202
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