Patient-derived osteosarcoma cells are resistant to methotrexate

Osteosarcoma is the most common primary bone tumor in children and young adults. The median survival of osteosarcoma patients has not significantly improved since 1990, despite administration of different classes of chemotherapy agents, such as methotrexate, cisplatin and doxorubicin. Cancer stem ce...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: dos Santos Cavalcanti, Amanda, Meohas, Walter, Ribeiro, Gabriele de Oliveira, de Sá Lopes, Ana Cristina, Gholamin, Sharareh, Razavi, Mostafa, Hanae Kasai Brunswick, Taís, Avan, Amir, Matheus Guimarães, João Antonio, Leite Duarte, Maria Eugenia, Kahn, Suzana Assad
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608286/
https://ncbi.nlm.nih.gov/pubmed/28934267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184891
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