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Changes in striatal activity and functional connectivity in a mouse model of Huntington's disease

Hereditary Huntington’s disease (HD) is associated with progressive motor, cognitive and psychiatric symptoms. A primary consequence of the HD mutation is the preferential loss of medium spiny projection cells with relative sparing of local interneurons in the striatum. In addition, among GABAergic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cabanas, Magali, Bassil, Fares, Mons, Nicole, Garret, Maurice, Cho, Yoon H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608247/
https://ncbi.nlm.nih.gov/pubmed/28934250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184580
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