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Automated computer-assisted quantitative analysis of intact murine lungs at the alveolar scale

Using state-of-the-art X-ray tomographic microscopy we can image lung tissue in three dimensions in intact animals down to a micrometer precision. The structural complexity and hierarchical branching scheme of the lung at this level of details, however, renders the extraction of biologically relevan...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lovric, Goran, Vogiatzis Oikonomidis, Ioannis, Mokso, Rajmund, Stampanoni, Marco, Roth-Kleiner, Matthias, Schittny, Johannes C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608210/
https://ncbi.nlm.nih.gov/pubmed/28934236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183979
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