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In vitro testing of basal cytotoxicity: establishment of an adverse outcome pathway from chemical insult to cell death
In this paper, an in vitro basal cytotoxicity testing strategy is described for new chemical entities that lack any pre-existing information on potential toxicity. Special attention is paid to the selection of the cellular system, cytotoxicity assay and exposure conditions. This approach is based on...
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| Vydáno v: | Toxicol In Vitro |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5608076/ https://ncbi.nlm.nih.gov/pubmed/27939612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2016.12.004 |
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