Dysregulated MicroRNA Expression and Chronic Lung Allograft Rejection in Recipients With Antibodies to Donor HLA

The pathogenesis of chronic rejection, Bronchiolitis Obliterans Syndrome (BOS) following lung transplantation (LT) is poorly understood. We hypothesized that development of antibodies to HLA (DSA) is associated with dysregulation of microRNA (miRNA) that predisposes BOS. Towards this, miRNA profilin...

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Pubblicato in:Am J Transplant
Autori principali: Xu, Z., Nayak, D., Yang, W., Baskaran, G., Ramachandran, S., Sarma, N., Aloush, A., Trulock, E., Hachem, R., Patterson, G. A., Mohanakumar, T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607954/
https://ncbi.nlm.nih.gov/pubmed/25649290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13185
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