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An In Vitro Caseum Binding Assay that Predicts Drug Penetration in Tuberculosis Lesions

The eradication of tuberculosis disease requires drug regimens that can penetrate the multiple layers of complex pulmonary lesions. Drug distribution in the caseous cores of cavities and lesions is especially crucial because they harbor subpopulations of drug-tolerant bacteria also commonly referred...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Sarathy, Jansy P., Liang, Hsin-pin Ho, Weiner, Danielle, Gonzales, Jacqueline, Via, Laura E., Dartois, Véronique
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607931/
https://ncbi.nlm.nih.gov/pubmed/28518128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55559
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