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Regulation of cytotoxic T-cell responses by p53 in cancer

An intriguing aspect of the tumor suppressor p53 is its ability to communicate to the adaptive immune system and control the cytotoxic T-lymphocyte (CTL) response to cancer cells. Wild-type p53 (wtp53) communicates with CTLs through proteins involved in the major histocompatibility complex (MHC) cla...

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Publicat a:Transl Cancer Res
Autors principals: Braun, Mitchell W., Iwakuma, Tomoo
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607642/
https://ncbi.nlm.nih.gov/pubmed/28944167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tcr.2016.11.76
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