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Serotonin 5-HT6 receptors affect cognition in a mouse model of Alzheimer’s disease by regulating cilia function

BACKGROUND: Serotonin receptor 5-HT6 is involved in cognition and Alzheimer’s disease (AD) development. However, the mechanism of 5-HT6 in AD pathology is not clear. METHODS: Since 5-HT6 is almost exclusively expressed in the primary cilia, using immunostaining we examined the number of cilia in the...

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Vydáno v:Alzheimers Res Ther
Hlavní autoři: Hu, Lili, Wang, Bingjie, Zhang, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607612/
https://ncbi.nlm.nih.gov/pubmed/28931427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-017-0304-4
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