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Complement C3 as a Prompt for Human Macrophage Death during Infection with Francisella tularensis Strain SCHU S4

Tularemia is caused by the Gram-negative bacterial pathogen Francisella tularensis. Infection of macrophages and their subsequent death are believed to play important roles in the progression of disease. Because complement is a particularly effective opsonin for Francisella, we asked whether complem...

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Pubblicato in:Infect Immun
Autori principali: Brock, Susan R., Parmely, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607423/
https://ncbi.nlm.nih.gov/pubmed/28739830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00424-17
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