Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6

The diversity of mesenchymal cell types in the lung that influence epithelial homeostasis and regeneration is poorly defined. We used genetic lineage tracing, single-cell RNA sequencing, and organoid culture approaches to show that Lgr5 and Lgr6, well-known markers of stem cells in epithelial tissue...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Lee, Joo-Hyeon, Tammela, Tuomas, Hofree, Matan, Choi, Jinwook, Marjanovic, Nemanja Despot, Han, Seungmin, Canner, David, Wu, Katherine, Paschini, Margherita, Bhang, Dong Ha, Jacks, Tyler, Regev, Aviv, Kim, Carla F.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607351/
https://ncbi.nlm.nih.gov/pubmed/28886383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.07.028
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