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Mild hypothermia provides Treg stability

Regulatory T cells (Tregs) play crucial role in maintenance of peripheral tolerance. Recent clinical trials confirmed safety and efficacy of Treg treatment of deleterious immune responses. However, Tregs lose their characteristic phenotype and suppressive potential during expansion ex vivo. Therefor...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Marek-Trzonkowska, Natalia, Piekarska, Karolina, Filipowicz, Natalia, Piotrowski, Arkadiusz, Gucwa, Magdalena, Vogt, Katrin, Sawitzki, Birgit, Siebert, Janusz, Trzonkowski, Piotr
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607276/
https://ncbi.nlm.nih.gov/pubmed/28931834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10151-1
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