THP-1-derived macrophages render lung epithelial cells hypo-responsive to Legionella pneumophila – a systems biology study

Immune response in the lung has to protect the huge alveolar surface against pathogens while securing the delicate lung structure. Macrophages and alveolar epithelial cells constitute the first line of defense and together orchestrate the initial steps of host defense. In this study, we analysed the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Schulz, Christine, Lai, Xin, Bertrams, Wilhelm, Jung, Anna Lena, Sittka-Stark, Alexandra, Herkt, Christina Elena, Janga, Harshavadhan, Zscheppang, Katja, Stielow, Christina, Schulte, Leon, Hippenstiel, Stefan, Vera, Julio, Schmeck, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607273/
https://ncbi.nlm.nih.gov/pubmed/28931863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12154-4
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