Hyperhomocysteinemia Alters Retinal Endothelial Cells Barrier Function and Angiogenic Potential via Activation of Oxidative Stress

Hyperhomocysteinemia (HHcy) is associated with several human visual disorders, such as diabetic retinopathy (DR) and age-related macular degeneration (AMD). Breakdown of the blood-retinal barrier (BRB) is linked to vision loss in DR and AMD. Our previous work revealed that HHcy altered BRB in retina...

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Udgivet i:Sci Rep
Main Authors: Mohamed, Riyaz, Sharma, Isha, Ibrahim, Ahmed S., Saleh, Heba, Elsherbiny, Nehal M., Fulzele, Sadanand, Elmasry, Khaled, Smith, Sylvia B., Al-Shabrawey, Mohamed, Tawfik, Amany
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607263/
https://ncbi.nlm.nih.gov/pubmed/28931831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09731-y
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