Hyperhomocysteinemia Alters Retinal Endothelial Cells Barrier Function and Angiogenic Potential via Activation of Oxidative Stress

Hyperhomocysteinemia (HHcy) is associated with several human visual disorders, such as diabetic retinopathy (DR) and age-related macular degeneration (AMD). Breakdown of the blood-retinal barrier (BRB) is linked to vision loss in DR and AMD. Our previous work revealed that HHcy altered BRB in retina...

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Pubblicato in:Sci Rep
Autori principali: Mohamed, Riyaz, Sharma, Isha, Ibrahim, Ahmed S., Saleh, Heba, Elsherbiny, Nehal M., Fulzele, Sadanand, Elmasry, Khaled, Smith, Sylvia B., Al-Shabrawey, Mohamed, Tawfik, Amany
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607263/
https://ncbi.nlm.nih.gov/pubmed/28931831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09731-y
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